According to researchers of the Penn
State College of Medicine, understanding how the virus kills cancer
cells may lead to new treatments for breast cancer.
Adeno-associated virus type 2 (AAV2) infects humans but is not known to cause sickness.
"Treatment
of breast cancer remains difficult because there are multiple signaling
pathways that promote tumour growth and develop resistance to
treatment," said Craig Meyers, professor of microbiology and immunology
at Pennsylvania State University in US.
In prior studies, the
researchers tested the virus on a variety of breast cancers that
represent degrees of aggressiveness on human papillomavirus-positive
cervical cancer cells.
The virus initiated apoptosis natural cell death in cancer cells without affecting healthy cells.
Treatment
of breast cancer differs from patient to patient due to differences in
tumours. A triple-negative breast cancer is typically aggressive.
"There
is an urgent and ongoing need for the development of novel therapies
which efficiently target triple-negative breast cancers," Meyers said.
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